92356-70-2

Upstream product

• 623-43-8 crotonic acid methyl ester 
• 1117-71-1 methyl-4-bromo-2-butenoate 
• 873-73-4 4-n-chlorophenylacetylene 
• 292638-85-8 acrylic acid methyl ester 
• 78704-49-1 1-(4-chlorophenyl)-2-trimethylsilylacetylene 
• 104-88-1 4-chlorobenzaldehyde 
• 1075-77-0 (E)-4-chlorocinnamic aldehyde 
• 67629-62-3 methyl 4-(diethylphosphono)crotonate 
• 15542-34-4 5-(4-chlorophenyl)penta-(2E,4E)-dienoic acid 

Downstream Products

• 15542-34-4 5-(4-chlorophenyl)penta-(2E,4E)-dienoic acid 
• 443360-62-1 (2E,4E)-5-(4-Chloro-phenyl)-penta-2,4-dienoyl chloride 
• 66110-17-6 (2E,4E)-5-(4-chlorophenyl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 

Relevant academic research and scientific papers

Microwave-accelerated Ru-catalyzed hydrovinylation of alkynes and enynes: A straightforward approach toward 1,3-dienes and 1,3,5-trienes

Quick, but not dirty! Microwave heating was found to have a significant effect on the Ru-catalyzed hydrovinylations of alkynes. A broad range of different terminal alkynes were coupled to methyl acrylate within just 30min in good to excellent yields (see scheme). This new protocol was transferred to the hydrovinylation of enynes as novel coupling partners in C-H-activation chemistry giving different 1,3,5-trienes as the sole products. Copyright

Synthetic and spectroscopic studies of structural analogs of piper amides - The 5-aryl-2E,4E-pentadienamides

The methyl esters and piperidides of fourteen 5-aryl-2E,4E-pentadienoic acids have been synthesized starting from the corresponding aryl aldehydes.

Substituent Effects on Carbon-13 NMR Chemical Shifts of Side-chain Carbons in 5-Aryl-2E,4E-pentadienoic Acid Derivatives

The 13C NMR spectra of two series of 5-aryl-2E,4E-pentadienoic acid derivatives, viz. the methyl esters and piperidides have been determined.The chemical shifts of C-2 and C-4 show very good correlations with the Hammett ?+-constants for all the substituents investigated, except for the para-nitro group which is capable of excerting a strong -R effect.A possible explanation for this has been advanced.Hammett correlations between substituents and the chemical shifts of both C-3 and C-5 carbons using ?0 parameters are less satisfactory.A reverse chemical shift effect has been observed for these two centres.