923565-74-6 Usage
Molecular class
Piperazinecarboxylic acids
Specific ester
4-[[4-[2-[4-[(3-fluorophenyl)aMino]-1-piperidinyl]-2-oxoethyl]phenyl]Methyl]-2-Methyl-1,1-diMethylethyl ester
Stereoisomer
(2S)-configuration
Piperazine ring
A six-membered heterocyclic ring with four nitrogen atoms and two carbon atoms
Phenyl group
A six-membered carbon ring with alternating single and double bonds
Fluorophenyl group
A phenyl group substituted with a fluorine atom at the 3-position
Amino group
A nitrogen atom bonded to two hydrogen atoms (-NH2)
Piperidinyl group
A six-membered carbon ring with one nitrogen atom in the 1-position
Oxo (carbonyl) group
A carbon-oxygen double bond (C=O)
Methyl ester group
An ester formed from the reaction of a carboxylic acid with methanol (-COOCH3)
Methyl group
A carbon atom bonded to three hydrogen atoms (-CH3)
Potential pharmaceutical applications
The compound may have various uses in the pharmaceutical industry, depending on its specific formulations and chemical contexts.
Properties
The properties of 1-Piperazinecarboxylic acid, 4-[[4-[2-[4-[(3-fluorophenyl)aMino]-1-piperidinyl]-2-oxoethyl]phenyl]Methyl]-2-Methyl-, 1,1-diMethylethyl ester, (2S)can vary depending on its chemical environment and specific formulations. However, some general properties may include solubility, stability, and reactivity with other compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 923565-74-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,3,5,6 and 5 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 923565-74:
(8*9)+(7*2)+(6*3)+(5*5)+(4*6)+(3*5)+(2*7)+(1*4)=186
186 % 10 = 6
So 923565-74-6 is a valid CAS Registry Number.
923565-74-6Relevant articles and documents
Discovery of N-(3-fluorophenyl)-1-[(4-([(35)-3-methyl-1-piperazinyl]methyl) phenyl)acetyl]-4-piperidinamine (GSK962040), the first small molecule motilin receptor agonist clinical candidate
Westaway, Susan M.,Brown, Samantha L.,Fell, Stephen C. M.,Johnson, Christopher N.,MacPherson, David T.,Mitchell, Darren J.,Myatt, James W.,Stanway, Steven J.,Seal, Jon T.,Stemp, Geoffrey,Thompson, Mervyn,Lawless, Kirk,McKay, Fiona,Muir, Alison I.,Barford, Jonathan M.,Cluff, Chermaine,Mahmood, Sadhia R.,Matthews, Kim L.,Mohamed, Shiyam,Smith, Beverley,Stevens, Alexander J.,Bolton, Victoria J.,Jarvie, Emma M.,Sanger, Gareth J.
experimental part, p. 1180 - 1189 (2010/01/16)
N-(3-Fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl) acetyl]-4-piperidinamine 12 (GSK962040) is a novel small molecule motilin receptor agonist. It possesses excellent activity at the recombinant human motilin receptor and also at the native rabbit motilin receptor where its agonist activity results in potentiation of the amplitude of neuronal-mediated contractions of isolated gastric antrum tissue. Compound 12 also possesses highly promising pharmacokinetic profiles in both rat and dog, and these results, in combination with further profiling in human native tissue and an in vivo model of gastrointestinal transit in the rabbit, have led to its selection as a candidate for further development.
