923565-73-5 Usage
Molecular weight
313.38 g/mol The mass of one mole of the compound, based on the atomic weights of its constituent atoms.
Ester functional group
The compound contains an ester group (-COO-) formed by the combination of a carboxylic acid and an alcohol.
Piperazine core
The compound has a piperazine ring (a six-membered nitrogen-containing ring) as its central structural feature.
Substitution pattern
The piperazine ring is substituted with a carboxyl group (-COOH) at position 1 and a phenylmethyl group (C6H4-CH2-) at position 4.
Chiral center
The compound has a chiral carbon atom (marked as (2S)) which means it can exist in two different enantiomeric forms.
Uses in pharmaceuticals
The compound is commonly used as an intermediate in the synthesis of various drugs, potentially providing a basis for the development of new medications.
Potential applications
The unique structure and properties of the compound may make it useful in organic chemistry and medicinal chemistry, as well as in various scientific and industrial fields. Further research and development could uncover new uses and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 923565-73-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,3,5,6 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 923565-73:
(8*9)+(7*2)+(6*3)+(5*5)+(4*6)+(3*5)+(2*7)+(1*3)=185
185 % 10 = 5
So 923565-73-5 is a valid CAS Registry Number.
923565-73-5Relevant academic research and scientific papers
Discovery of N-(3-fluorophenyl)-1-[(4-([(35)-3-methyl-1-piperazinyl]methyl) phenyl)acetyl]-4-piperidinamine (GSK962040), the first small molecule motilin receptor agonist clinical candidate
Westaway, Susan M.,Brown, Samantha L.,Fell, Stephen C. M.,Johnson, Christopher N.,MacPherson, David T.,Mitchell, Darren J.,Myatt, James W.,Stanway, Steven J.,Seal, Jon T.,Stemp, Geoffrey,Thompson, Mervyn,Lawless, Kirk,McKay, Fiona,Muir, Alison I.,Barford, Jonathan M.,Cluff, Chermaine,Mahmood, Sadhia R.,Matthews, Kim L.,Mohamed, Shiyam,Smith, Beverley,Stevens, Alexander J.,Bolton, Victoria J.,Jarvie, Emma M.,Sanger, Gareth J.
experimental part, p. 1180 - 1189 (2010/01/16)
N-(3-Fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl) acetyl]-4-piperidinamine 12 (GSK962040) is a novel small molecule motilin receptor agonist. It possesses excellent activity at the recombinant human motilin receptor and also at the native rabbit motilin receptor where its agonist activity results in potentiation of the amplitude of neuronal-mediated contractions of isolated gastric antrum tissue. Compound 12 also possesses highly promising pharmacokinetic profiles in both rat and dog, and these results, in combination with further profiling in human native tissue and an in vivo model of gastrointestinal transit in the rabbit, have led to its selection as a candidate for further development.
