923568-89-2

Basic information

• Product Name: tert-butyl 5-methoxy-2-oxo-3-phenylindoline-1-carboxylate
• Synonyms: tert-butyl 5-methoxy-2-oxo-3-phenylindoline-1-carboxylate
• CAS NO: 923568-89-2
• Molecular Weight: 339.391
• Mol File: 923568-89-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl 5-methoxy-2-oxo-3-phenylindoline-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 5-methoxy-2-oxo-3-phenylindoline-1-carboxylate(923568-89-2)
• EPA Substance Registry System: tert-butyl 5-methoxy-2-oxo-3-phenylindoline-1-carboxylate(923568-89-2)

Safety Data

• Hazardous Substances Data: 923568-89-2(Hazardous Substances Data)

Upstream product

• 15757-31-0 5-methoxy-3-phenyl-2-indolinone 
• 24424-99-5 di-tert-butyl dicarbonate 
• 100-58-3 phenylmagnesium bromide 
• 39755-95-8 5-methoxyisatine 
• 28864-73-5 3-hydroxy-5-methoxy-3-phenylindolin-2-one 
• 1040749-58-3 1-(t-butoxycarbonyl)-2-oxo-5-methoxy-3-phenylindolin-3-yl t-butyl carbonate 

Downstream Products

• 1399290-33-5 (R)-tert-butyl-3-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)-5-methoxy-2-oxo-3-phenylindoline-1-carboxylate 
• 1380195-73-2 (R)-tert-butyl 5-methoxy-3-((R)-2-nitro-1-(p-tolyl)ethyl)-2-oxo-3-phenylindoline-1-carboxylate 
• 1040749-33-4 (S)-tert-butyl 3-fluoro-5-methoxy-2-oxo-3-phenylindoline-1-carboxylate 
• 1352614-22-2 C₂₈H₂₉NO₆S 
• 1273020-54-4 (S)-tert-butyl 3-chloro-5-methoxy-2-oxo-3-phenylindoline-1-carboxylate 
• 1335112-37-2 (R)-tert-butyl 3-chloro-5-methoxy-2-oxo-3-phenylindoline-1-carboxylate 
• 1271489-34-9 tert-butyl (S)-3-(benzoyloxy)-5-methoxy-2-oxo-3-phenylindoline-1-carboxylate 
• 1257767-63-7 di-tert-butyl 1-((R)-1-(tert-butoxycarbonyl)-5-methoxy-2-oxo-3-phenylindolin-3-yl)hydrazine-1,2-dicarboxylate 
• 1197418-14-6 C₂₈H₂₈N₂O₆ 
• 1175713-27-5 C₂₄H₂₇NO₅ 
• 1422007-72-4 C₂₀H₂₁NO₅ 
• 1393945-47-5 (R)-tert-butyl 5-methoxyl-2-oxo-3-phenyl-3-(phenylthio)indoline-1-carboxylate 

Relevant articles and documents

Organocatalytic stereoselective conjugate addition of 3-substituted oxindoles with in situ generated ortho-quinone methides

A novel method for the stereoselective conjugate addition of 3-substituted oxindoles to in situ generated o-QMs was described. This process was catalyzed efficiently by a cinchonidine-derived squaramide catalyst in oil-water phase, furnishing the corresponding 3,3-disubsituted oxindole derivatives in moderate to high yields (up to 98%) with high stereoselectivities (up to 95% ee, 15.4:1 dr). The utility of this reaction was also investigated by the gram-scale synthesis and derivatization of one of the products.

Cinchona alkaloid catalyzed enantioselective fluorination of allyl silanes, silyl enol ethers, and oxindoles

(Chemical Equation Presented) Catalytic variant: Allyl silanes and silyl enol ethers 1 are good substrates for the catalytic highly enantioselective fluorodesilylation using a combination of a biscinchona alkaloid, N-fluorobenzenesulfonimide (NFSI), and base (see scheme). Pharmaceutically attractive 3-aryl-3-fluorooxindoles such as 3 can also be synthesized with high enantioselectivity.