923570-22-3

Upstream product

• 200004-40-6 (S)-3-chloro-1-(4-fluorophenyl)propan-1-ol 
• 347-93-3 3-chloro-4'-fluoropropiophenone 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 926657-20-7 (3S,4R)-4-(4-Benzyloxy-phenyl)-3-(4-fluoro-phenyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-azetidin-2-one 
• 926657-23-0 (S)-1-(4-Fluoro-phenyl)-3-iodo-propan-1-ol 
• 926657-24-1 (3S,4R)-4-(4-Benzyloxy-phenyl)-3-(4-fluoro-phenyl)-azetidin-2-one 

Relevant academic research and scientific papers

NOVEL SUBSTITUTED AZETIDINONES

Novel azetidinones and pharmaceutical compositions are described, as are the methods of using such compounds and compositions to treat subjects, including humans, suffering from hyperlipidemia, hypercholesterolemia, hypertriglyceridemia and atherosclerosi

Ezetimibe analogs with a reorganized azetidinone ring: Design, synthesis, and evaluation of cholesterol absorption inhibitions

The underlying principle of drug design in this paper is that the maximum retention of the functional groups that exist in the marketed drug would provide a higher probability for comparable safety while the conformational changes in the newly created ana