923580-07-8Relevant articles and documents
On the mechanism of an asymmetric α,β-unsaturated carboxylic acid hydrogenation: Application to the synthesis of a PGD2 receptor antagonist
Tellers, David M.,McWilliams, J. Christopher,Humphrey, Guy,Journet, Michel,DiMichele, Lisa,Hinksmon, Joseph,McKeown, Arlene E.,Rosner, Thorsten,Sun, Yongkui,Tillyer, Richard D.
, p. 17063 - 17073 (2006)
Ruthenium complexes employing axially chiral ligands were found to be effective asymmetric hydrogenation catalysts for the reduction of α,β-unsaturated ene acid 1-E to give 2, a prostaglandin D2 (PGD2) receptor antagonist. With [(S-B