923800-74-2

Basic information

• Product Name: 3-(thiophen-2-yl)-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
• Synonyms: 3-(thiophen-2-yl)-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
• CAS NO: 923800-74-2
• Molecular Weight: 228.274
• Mol File: 923800-74-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(thiophen-2-yl)-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(thiophen-2-yl)-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide(923800-74-2)
• EPA Substance Registry System: 3-(thiophen-2-yl)-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide(923800-74-2)

Safety Data

• Hazardous Substances Data: 923800-74-2(Hazardous Substances Data)

Upstream product

• 872-31-1 3-Bromothiophene 
• 201230-82-2 carbon monoxide 
• 28144-70-9 anthranilic acid amide 
• 498-62-4 3-thiophene carboxaldehyde 
• 13679-64-6 3-vinylthiophene 

Relevant articles and documents

Oxidative synthesis of quinazolinones and benzothiadiazine 1,1-dioxides from 2-aminobenzamide and 2-aminobenzenesulfonamide with benzyl alcohols and aldehydes

An interesting procedure for the zinc-catalyzed oxidative transformation of ready available 2-aminobenzamide, 2-aminobenzenesulfonamide with benzyl alcohols has been developed. Various quinazolinones and benzothiadiazine 1,1-dioxides were prepared in moderate to good yields under identical conditions. The reactions of both aromatic aldehydes and aliphatic aldehydes with 2-aminobenzamide under catalyst free conditions were described as well. In water media, the products were formed in good yields.

Synthesis method of 2-substituted heterocyclic ring quinazolinone compounds

The invention discloses a synthesis method of 2-substituted heterocyclic ring quinazolinone compounds. The reaction equation is as shown in the description, wherein a heterocyclic ring vinyl compoundin the reaction equation is as shown in the description. The synthesis method has the beneficial effects that (1) the reaction is efficient, the yield is high, reaction efficiency is higher after reaction is amplified, and the method is suitable for large-scale industrialized production; (2) the heterocyclic ring vinyl compound is selected as the raw material, is low in cost and easy to obtain, and is more economical; (3) the synthesis process is easy to operate, and the obtained product is easy for aftertreatment; and (4) the method is not performed at high temperature and high pressure, thereaction condition is mild and reaction time is short.