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(m, 1H), 8.09–8.13 (m, 1H), 12.2 (s, 1H, NH). 13C NMR (DMSO-
d6): d ¼ 14.8 (CH3), 22.9 (CH2), 27.7 (CH2), 29.1 (CH2), 31.8
(CH2), 35.4 (CH2), 121.7 (C), 126.6 (CH), 126.8 (CH), 127.7 (CH),
135.1 (CH), 149.9 (C), 158.4 (C), 162.8 (CO). GC-MS (EI, 70 eV):
m/z (%) [M+] 230 (5), 187 (11), 160 (100). HRMS (ESI): calc. for
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C
14H18N2O1: 230.14136; found: 230.14113.
2-Heptylquinazolin-4(3H)-one
1
Yield: (202 mg, 83%); H NMR (300 MHz, DMSO-d6): d ¼ 0.87
(t, J ¼ 7.30 Hz, 3H), 1.23–1.39 (m, 8H), 1.74 (Pent. 2H),
2.61 (t, J ¼ ,7.63 Hz, 2H), 7.44–7.49 (m, 1H), 7.60–7.63 (m, 1H),
7.78–7.81 (m, 1H), 8.09–8.13 (m, 1H), 12.2 (s, 1H, NH). 13C NMR
(DMSO-d6): d ¼ 14.8 (CH3), 23.0 (CH2), 27.8 (CH2), 29.3 (CH2),
29.5 (CH2), 32.1 (CH2), 35.5 (CH2), 121.7 (C), 126.6 (CH), 126.8
(CH), 127.7 (CH), 135.1 (CH), 149.9 (C), 158.8 (C), 163.1 (CO).
GC-MS (EI, 70 eV): m/z (%) [M+] 244 (5), 187 (10), 160 (100).
HRMS (ESI): calc. for C15H20N2O1: 244.15701; found: 244.15698.
2-Cyclohexylquinazolin-4(3H)-one
1
Yield: (141 mg, 62%); H NMR (300 MHz, DMSO-d6): d ¼ 1.21–
1.40 (m, 3H), 1.54–1.73 (3H), 1.79–1.96 (4H), 7.47 (t, J ¼ 7.45 Hz,
1H), 7.63 (d, J ¼ 8.40 Hz, 1H), 7.79 (d, J ¼ 7.45 Hz, 1H), 8.11 (d,
J ¼ 8.40 Hz, 1H), 12.1 (s, 1H, NH). 3C NMR (DMSO-d6): d ¼ 26.3
(CH2), 26.5 (2CH2), 31.2 (2CH2), 43.8 (CH), 121.9 (C), 126.6 (CH),
126.8 (CH), 127.9 (CH), 135.1 (CH), 149.9 (C), 161.7 (C),
162.9 (CO).
Notes and references
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