923948-91-8

Upstream product

• 923948-90-7 tert-butyl (3S,4S)-3-(benzyloxy)-4-hydroxy-4-phenylpiperidine-1-carboxylate 
• 74-88-4 methyl iodide 
• 100-39-0 benzyl bromide 
• 186347-72-8 4-phenyl-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 923948-92-9 tert-butyl (3S,4S)-3-hydroxy-4-methoxy-4-phenylpiperidine-1-carboxylate 

Relevant academic research and scientific papers

A highly selective monoalkylation of tert-butyl 3,4-dihydroxy-4- phenylpiperidine-1-carboxylate under phase transfer conditions

Liquid-liquid phase transfer conditions have been found to provide highly selective monoalkylation of tert-butyl 3,4-dihydroxy-4-phenylpiperidine-1- carboxylate, a transformation for which many other common alkylation protocols proved inadequate. The high

PIPERIDINOYL-PYRROLIDINE AND PIPERIDINOYL-PIPERIDINE COMPOUNDS

The present invention relates to a class of compounds of general formula (I) and the salts, hydrates, solvates, polymorphs and prodrugs wherein n, R6, R7 and R10 are as defined herein and especially to MCR4 agonist compounds of formula (I), to their use in medicine, particularly in the treatment of sexual dysfunction and obesity, to intermediates useful in their synthesis and to compositions containing them.