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Pyridazine, 6-chloro-4-methyl-3-(phenylmethyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

923951-11-5

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923951-11-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 923951-11-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,3,9,5 and 1 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 923951-11:
(8*9)+(7*2)+(6*3)+(5*9)+(4*5)+(3*1)+(2*1)+(1*1)=175
175 % 10 = 5
So 923951-11-5 is a valid CAS Registry Number.

923951-11-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-benzyl-6-chloro-4-methylpyridazine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:923951-11-5 SDS

923951-11-5Downstream Products

923951-11-5Relevant academic research and scientific papers

Discovery of NVP-LEQ506, a second-generation inhibitor of smoothened

Peukert, Stefan,He, Feng,Dai, Miao,Zhang, Rui,Sun, Yingchuan,Miller-Moslin, Karen,Mcewan, Michael,Lagu, Bharat,Wang, Kate,Yusuff, Naeem,Bourret, Aaron,Ramamurthy, Arun,Maniara, Wieslawa,Amaral, Adam,Vattay, Anthony,Wang, Anlai,Guo, Ribo,Yuan, Jing,Green, John,Williams, Juliet,Buonamici, Silvia,Kelleher, Joseph F.,Dorsch, Marion

supporting information, p. 1261 - 1265 (2013/08/23)

First disclosure: Continued optimization provided a novel type of Smoothened (Smo) antagonist based on a pyridazine core. The compound, NVP-LEQ506, currently in phaseI clinical trials, combines high intrinsic potency and good pharmacokinetic properties resulting in excellent efficacy in rodent tumor models of medulloblastoma. Activity against a Smo mutant conferring resistance observed in a previous clinical trial with a competitor compound suggests additional therapeutic potential.

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