923975-81-9

Usage

Structural Classification

Diazaspiro compound

Functional Groups

Chlorophenyl group (4-chlorophenyl)
Ketone group (at position 2)

Ring Structure

Spiro-fused nitrogen-containing six-membered ring

Applications

Pharmaceuticals: Potential medicinal applications due to its unique structural features and biological activities.
Agrochemicals: Possible uses in agriculture due to its properties.

Usage in Organic Synthesis

Building block for the synthesis of various biologically active molecules.

Scaffold for Drug Development

Valuable spiro-fused structure for the development of new drugs and bioactive compounds.

Overall Potential

Significant potential in medicinal and chemical research due to its structural and biological properties.

Upstream product

• 899926-57-9 3-(4-chlorophenyl)-1,4-diazaspiro[4.5]dec-3-ene-2-thione 
• 6212-33-5 2-(4-Chlorophenyl)glycine 
• 102333-75-5 2-amino-2-(4-chlorophenyl)acetamide 
• 108-94-1 cyclohexanone 
• 42718-19-4 dl-α-4-chlorophenylglycine methyl ester hydrochloride 

Relevant academic research and scientific papers

Glyt1 Transporter Inhibitors and Uses Thereof in Treatment of Neurological and Neuropsychiatric Disorders

The invention provides a compound of formula (I) or a solvate thereof: wherein R1, R2, R3, R4, R5, R6, and n are as defined in the specification, and uses of such compounds. The compounds i

GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS

Compounds of formula (I) or a salt thereof are provided wherein R1, R2, R6, R7, R8, R9 and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture

1-(2-ARYL-2-OXOETHYL)-3-PHENYL-1, 4-DIAZASPIRO [4.5]DEC-3-EN-2-ONE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORTER INHIBITORS

Novel acetophenone compounds of formula (I), compositions containing (I), processes for the preparation of (I), and use of (I) as inhibitors of the glycine transporter, are provided. Definitions of Ar, R5, R6, R7, R8

N-PHENYL-2-0X0-1,4-DIAZASPIR0 [4.5] DEC-3-EN-1-YL ACETAMIDE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORTER INHIBITORS

Compounds of formula (I) and salts and solvates are provided: Formula (I) Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention d