92421-42-6

Basic information

• Product Name: 1,3-dimethyl-2,4,5-trimethoxybenzene
• Synonyms: 1,3-dimethyl-2,4,5-trimethoxybenzene
• CAS NO: 92421-42-6
• Molecular Weight: 196.246
• Mol File: 92421-42-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,3-dimethyl-2,4,5-trimethoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dimethyl-2,4,5-trimethoxybenzene(92421-42-6)
• EPA Substance Registry System: 1,3-dimethyl-2,4,5-trimethoxybenzene(92421-42-6)

Safety Data

• Hazardous Substances Data: 92421-42-6(Hazardous Substances Data)

Upstream product

• 4380-94-3 3,5-dimethyl-1,2,4-benzenetriol 
• 77-78-1 dimethyl sulfate 
• 527-61-7 2,6-dimethyl-1,4-benzoquinone 
• 31404-86-1 2,4-dimethyl-3,6-dimethoxybenzaldehyde 
• 1025807-18-4 3,6-Dimethoxy-2,4-dimethyl-phenol 
• 74-88-4 methyl iodide 
• 41168-76-7 1,3-dimethyl-2,4,5-triacetoxybenzene 

Downstream Products

• 92421-43-7 2,4-dimethyl-3,5,6-trimethoxybenzaldehyde 
• 107301-82-6 2,4-dimethyl-3,5,6-trimethoxybenzyl chloride 
• 3214-57-1 2-methoxy-3,5-dimethyl-2,5-cyclohexadiene-1,4-dione 
• 1431987-16-4 10-(5-methoxy-2,4-dimethyl-3,6-dioxocyclohexa-1,4-dienyl)decyl nitrate 
• 1431987-13-1 6-(5-methoxy-2,4-dimethyl-3,6-dioxo cyclohexa-1,4-dienyl)hexyl nitrate 
• 1431987-18-6 8-(5-methoxy-2,4-dimethyl-3,6-dioxocyclohexa-1,4-dienyl)octyl nitrate 
• 107301-84-8 (2,3,5-trimethoxy-4,6-dimethylbenzyl)trimethylsilane 
• 107301-77-9 2,4-dimethyl-3,5,6-trimethoxybenzyl alcohol 
• 144562-72-1 8-Pyridin-3-yl-2-[1-(2,3,5-trimethoxy-4,6-dimethyl-phenyl)-meth-(E)-ylidene]-octanoic acid ethyl ester 
• 144562-64-1 7-Pyridin-3-yl-2-[1-(2,3,5-trimethoxy-4,6-dimethyl-phenyl)-meth-(E)-ylidene]-heptanoic acid ethyl ester 
• 144562-90-3 (E)-3-(2,3,5-trimethoxy-4,6-dimethylphenyl)-2-[6-(3-pyridyl)hexyl]-2-propenoic acid 
• 144562-81-2 (E)-3-(2,3,5-Trimethoxy-4,6-dimethylphenyl)-2-[5-(pyridin-3-yl)pentyl]-2-propenoic acid 
• 144563-00-8 (E)-3-(2-Methoxy-3,5-dimethyl-1,4-benzoquinon-6-yl)-2-[5-(pyridin-3-yl)pentyl]-2-propenoic acid 

Relevant articles and documents

QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE

The present invention relates to novel nitric oxide donor compounds for the use in the treatment and/or prophylaxis of hypertensive glaucoma, normotensive glaucoma and ocular hypertension.

Synthesis and characterization of mitoQ and idebenone analogues as mediators of oxygen consumption in mitochondria

Analogues of mitoQ and idebenone were synthesized to define the structural elements that support oxygen consumption in the mitochondrial respiratory chain. Eight analogues were prepared and fully characterized, then evaluated for their ability to support oxygen consumption in the mitochondrial respiratory chain. While oxygen consumption was strongly inhibited by mitoQ analogues 2-4 in a chain length-dependent manner, modification of idebenone by replacement of the quinone methoxy groups by methyl groups (analogues 6-8) reduced, but did not eliminate, oxygen consumption. Idebenone analogues 6-8 also displayed significant cytoprotective properties toward cultured mammalian cells in which glutathione had been depleted by treatment with diethyl maleate.

Structure-activity relationships of (E)-3-(1,4-benzoquinonyl)-2-[(3- pyridyl)alkyl]-2-propenoic acid derivatives that inhibit both 5-lipoxygenase and thromboxane A2 synthetase

As part of our research for the development of novel antiinflammatory drug candidates, we have designed and synthesized a series of (E)-3-(1,4- benzoquinonyl)-2-[(3-pyridyl)alkyl]-2-propenoic acid derivatives as dual inhibitors of 5-lipoxygenase (5-LO) an