92422-79-2

Usage

Uses

Used in Pharmaceutical Industry:
2-M-TOLYL-THIAZOLE-4-CARBALDEHYDE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs and enhance the properties of existing ones.
Used in Agrochemical Industry:
In the agrochemical sector, 2-M-TOLYL-THIAZOLE-4-CARBALDEHYDE is utilized as an intermediate in the production of agrochemicals, playing a crucial role in the formulation of pesticides and other agricultural chemicals to improve crop protection and yield.
Used in Dye and Pigment Manufacturing:
2-M-TOLYL-THIAZOLE-4-CARBALDEHYDE is employed as a building block in the manufacturing of dyes and pigments, contributing to the creation of a wide range of colorants used in various industries, including textiles, plastics, and printing inks.
Used in Functional Materials Production:
2-M-TOLYL-THIAZOLE-4-CARBALDEHYDE is also used as a component in the production of functional materials, where its unique properties can be leveraged to develop materials with specific characteristics for use in various applications, such as sensors, batteries, or other advanced technologies.
Used in Research and Development:
2-M-TOLYL-THIAZOLE-4-CARBALDEHYDE is utilized in research and development for its potential biological and pharmacological activities, including antimicrobial and antifungal properties, which could lead to the discovery of new therapeutic agents or applications in healthcare and related fields.

InChI:InChI=1/C11H9NOS/c1-8-3-2-4-9(5-8)11-12-10(6-13)7-14-11/h2-7H,1H3

Upstream product

• 89152-40-9 4-(iodomethyl)-2-(m-tolyl)thiazole 
• 2362-63-2 3-methylthiobenzamide 
• 534-07-6 1,3-Dichloroacetone 
• 41963-17-1 4-chloromethyl-2-m-tolyl-thiazole 

Downstream Products

• 21166-39-2 1-(2-m-tolyl-thiazol-4-yl)-ethanone 
• 138019-76-8 (Z)-1-(2-Hydroxy-phenyl)-3-(2-m-tolyl-thiazol-4-yl)-propenone 
• 116227-89-5 (Z)-1-Phenyl-3-(2-m-tolyl-thiazol-4-yl)-propenone 
• 1637585-09-1 N-(1-(2-m-tolylthiazol-4-yl)ethyl)butyramide 
• 1637585-13-7 N-(1-(2-m-tolylthiazol-4-yl)ethyl)butyramide 
• 1637585-17-1 1-(2-m-tolylthiazol-4-yl)ethanamine 
• 1637585-21-7 1-(2-m-tolylthiazol-4-yl)ethanamine 
• 1637585-01-3 C₁₂H₁₂N₄S 
• 1637585-05-7 N-(1-(2-m-tolylthiazol-4-yl)ethyl)butyramide 
• 1177474-03-1 1-(2-m-tolylthiazol-4-yl)ethanamine 
• 1585214-68-1 rac-ethyl 3-hydroxy-3-(2-m-tolylthiazol-4-yl)propanoate 
• 1585214-84-1 (R)-ethyl 3-hydroxy-3-(2-m-tolylthiazol-4-yl)propanoate 
• 1585214-80-7 (S)-ethyl 3-hydroxy-3-(2-m-tolylthiazol-4-yl)propanoate 
• 1585214-88-5 (S)-2-(ethoxycarbonyl)-1-(2-m-tolylthiazol-4-yl)ethyl butanoate 

Relevant academic research and scientific papers

Heterocycles 38. Biocatalytic synthesis of new heterocyclic mannich bases and derivatives

This paper describes the biocatalytic synthesis of new Mannich bases containing various heterocyclic rings (thiazole, furane, thiophene, pyridine) by applying the lipase catalyzed trimolecular condensation of the corresponding heterocyclic aldehydes with acetone and primary aromatic amines, in mild and eco-friendly reaction conditions. The obtained Mannich bases were acylated to their corresponding N-acetyl derivatives. All compounds were characterized by 1H-NMR, 13C-NMR and MS spectrometry.

Heterocycles 32. Efficient kinetic resolution of 1-(2-arylthiazol-4-yl) ethanols and their acetates using lipase B from Candida antarctica

In this paper we describe the chemoenzymatic synthesis of new enantiomerically enriched (R)- and (S)-1-(2-arylthiazol-4-yl)ethanols and their acetates by enzymatic enantioselective acetylation of the racemic alcohols rac-2a-d and by methanolysis of the corresponding racemic esters rac-3a-d mediated by lipase B from Candida antarctica (CaL-B) in non-aqueous media. In terms of stereoselectivity and activity, both procedures, acylation and alcoholysis, gave similar good results (50% conversion, E 〉 200). The absolute configuration of the kinetic resolution products was determined by a detailed 1H NMR study of the Mosher's derivatives of (S)-2b.