924281-89-0Relevant academic research and scientific papers
Synthesis and biological evaluation of novel 1-deoxy-1-[6-[((hetero) arylcarbonyl)hydrazino]-9H-purin-9-yl]-N-ethyl-β-D-ribofuranuronamide derivatives as useful templates for the development of A2B adenosine receptor agonists
Baraldi, Pier Giovanni,Preti, Delia,Tabrizi, Mojgan Aghazadeh,Fruttarolo, Francesca,Romagnoli, Romeo,Carrion, Maria Dora,Lopez Cara, Luisa Carlota,Moorman, Allan R.,Varani, Katia,Borea, Pier Andrea
, p. 374 - 380 (2007)
The lack of molecules endowed with selective and potent agonistic activity toward the hA2B adenosine receptors has limited the studies on this pharmacological target and consequently the evaluation of its therapeutic potential. We report the de
ADENOSINE A2B RECEPTOR AGONISTS
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Page/Page column 12, (2008/06/13)
The present invention provides compounds of the formula wherein R1, R2, R3 and n have meaning as described in the specification, as adenosine A2B receptor agonists and, thus, may be employed for the treatment of
