92446-06-5Relevant academic research and scientific papers
Synthesis, antibacterial activities, and sustained perfume release properties of optically active5-hydroxy- And 5-acetoxyalkanethioamide analogues
Shimotori, Yasutaka,Hoshi, Masayuki,Ogawa, Narihito,Miyakoshi, Tetsuo,Kanamoto, Taisei
, p. 84 - 98 (2020/07/03)
5-Acetoxy- and 5-hydroxyalkanethioamide analogues showed high antibacterial activity against Staphylococcus aureus. Antibacterial thioamides were prepared from 5-alkyl-δ-lactones by amidation, thionation, and subsequent deacetylation. Optically active thioamides with 99% diastereomeric excesses were prepared by diastereomeric resolution using Cbz-L-proline as the resolving agent. Antibacterial thioamides were slowly lactonized by a lipase catalyst. Therefore, these thioamides are potential sustained-release perfume compounds having antibacterial properties.
Catalytic oxidation of alkyl- and cycloalkylcyclanones into lactones
Abbasov,Alimardanov,Suleimanova
, p. 621 - 626 (2007/10/03)
Pilot-plant syntheses of alkyl and cycloalkylcyclanones and their subsequent liquid-phase oxidation into lactones are described. Characteristics of resulting intermediates and target products are reported.
