924654-86-4

Upstream product

• 185999-03-5 6-(trityloxy)hex-1-en 
• 924654-74-0 (S)-Hydroxy-phenyl-acetic acid (R)-1-bromomethyl-5-trityloxy-pentyl ester 
• 150-76-5 4-methoxy-phenol 

Downstream Products

• 924654-87-5 Methanesulfonic acid (R)-1-(4-methoxy-phenoxymethyl)-5-trityloxy-pentyl ester 

Relevant academic research and scientific papers

Single enantiomer epoxides by bromomandelation of prochiral alkenes

A combination of mandelic acid and N-bromosuccinimide efficiently converts prochiral alkenes into a readily separable 1:1 mixture of the bromomandelates. The diastereomerically pure bromomandelates are then converted into a variety of enantiomerically pure products. Terminal alkenes are converted into enantiomerically pure epoxides. Cyclohexene is converted into enantiomerically pure cis-2-azidocyclohexanol and cis-2-phenylthiocyclohexanol.