924654-74-0Relevant academic research and scientific papers
Single enantiomer epoxides by bromomandelation of prochiral alkenes
Taber, Douglass F.,Liang, Jiang-Lin
, p. 431 - 434 (2007/10/03)
A combination of mandelic acid and N-bromosuccinimide efficiently converts prochiral alkenes into a readily separable 1:1 mixture of the bromomandelates. The diastereomerically pure bromomandelates are then converted into a variety of enantiomerically pure products. Terminal alkenes are converted into enantiomerically pure epoxides. Cyclohexene is converted into enantiomerically pure cis-2-azidocyclohexanol and cis-2-phenylthiocyclohexanol.
