92473-54-6 Usage
General Description
2,3-Quinoxalinedione, 1,4-dihydro-1,6-dimethyl (9CI), also known as alpha-ketoglutaramic acid, is a chemical compound with the molecular formula C8H10N2O2. It is a cyclic derivative of oxalic acid and is commonly used in the synthesis of pharmaceuticals and agrochemicals. 2,3-Quinoxalinedione,1,4-dihydro-1,6-dimethyl-(9CI) is a yellowish solid with a molecular weight of 166.18 g/mol and a melting point of 188-192°C. It is a versatile building block in organic synthesis, with applications in the production of antitumor, anticonvulsant, and antimicrobial compounds. Additionally, it can be used as a reagent in chemical research and as an intermediate in the manufacturing of heterocyclic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 92473-54-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,4,7 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 92473-54:
(7*9)+(6*2)+(5*4)+(4*7)+(3*3)+(2*5)+(1*4)=146
146 % 10 = 6
So 92473-54-6 is a valid CAS Registry Number.
92473-54-6Relevant articles and documents
1,2,4-Triazolo[4,3-a]quinoxaline-1,4-diones as antiallergic agents
Loev,Musser,Brown,Jones,Kahen,Huang,Khandwala,Sonnino-Goldman,Leibowitz
, p. 363 - 366 (1985)
A series of new 1,4-dihydro-1,2,4-triazolo[4,3-a]quinoxaline-1,4-diones has been reported. These compounds were tested as inhibitors of antigen-induced release of histamine (AIR) in vitro from rat peritoneal mast cells (RMC) and as inhibitors of IgE-mediated rat passive cutaneous anaphylaxis (PCA). Most of this new class of antiallergic agents showed good activity in the RMC and PCA tests. The most potent compound, 2-acetyl-7-chloro-5-n-propyl-1,2,4-triazolo[4,3-a]quinoxaline-1,4-dione, with an I50 value of 0.1 μM, is 30 times more potent than disodium cromoglycate (DSCG) in the RMC assay.
