92474-80-1

Basic information

• Product Name: 4-METHYLENE-1,3-DIOXASPIRO[4.5]DECAN-2-ONE
• Synonyms: 4-METHYLENE-1,3-DIOXASPIRO[4.5]DECAN-2-ONE;4-METHYLENE-1,3-DIOXASPIRO[4.5]DECANE-2-ONE;5'-Methylenespiro[cyclohexane-1,4'-[1,3]dioxolan]-2'-one
• CAS NO: 92474-80-1
• Molecular Formula: C₉H₁₂O₃
• Molecular Weight: 168.19
• Mol File: 92474-80-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 228.9°Cat760mmHg
• Flash Point: 96°C
• Appearance: /
• Density: 1.15g/cm³
• Vapor Pressure: 0.0717mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: 4-METHYLENE-1,3-DIOXASPIRO[4.5]DECAN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYLENE-1,3-DIOXASPIRO[4.5]DECAN-2-ONE(92474-80-1)
• EPA Substance Registry System: 4-METHYLENE-1,3-DIOXASPIRO[4.5]DECAN-2-ONE(92474-80-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 92474-80-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H12O3/c1-7-9(12-8(10)11-7)5-3-2-4-6-9/h1-6H2

Upstream product

• 124-38-9 carbon dioxide 
• 78-27-3 1-Ethynylcyclohexan-1-ol 

Downstream Products

• 311788-11-1 4-hydroxy-4-methyl-3-phenethyl-1-oxa-3-aza-spiro[4.5]decan-2-one 
• 934672-16-9 4-hydroxy-3-[2-(3,4-dimethoxyphenyl)ethyl]-4-methyl-1-oxa-3-azaspiro[4.5]decan-2-one 

Relevant articles and documents

Effective guanidine-catalyzed synthesis of carbonate and carbamate derivatives from propargyl alcohols in supercritical carbon dioxide

The reactions of propargyl alcohols with carbon dioxide in supercritical carbon dioxide or in acetonitrile with gaseous carbon dioxide in the presence of organic bases as catalysts have been examined. Bicyclic guanidines are effective catalysts for the formation of α-methylene cyclic carbonates under mild reaction conditions. Oxoalkyl carbonates, oxoalkyl carbamates or α-methyleneoxazolidinones are obtained in high yields and good selectivities in one-step starting from propargyl alcohols and an external nucleophile (alcohols or amines) using bicyclic guanidines as catalysts in supercritical carbon dioxide. Propargylic diols under the same reaction conditions underwent a rearrangement process instead of carbon dioxide insertion whereas in the presence of an external nucleophile the formation of oxocarbonates, oxocarbamates or cyclic carbamates was achieved in satisfactory yields.