92487-01-9Relevant academic research and scientific papers
Ketene-S,N-acetals as Synthetic Intermediates for Heterocycles. New Synthesis of Multisubstituted Pyridine-2-thiones
Takahata, Hiroki,Wang, Eng-Chi,Nakajima, Tomoko,Yamazaki, Takao
, p. 3139 - 3145 (2007/10/02)
Ketene-S,N-acetals reacted with isothiocyanates to give β-aminothiocarbonyl-α-methylthioenamines, which were transformed into enaminonitriles by carbon-carbon bond formation with malononitriles.Treatment of the enaminonitriles with base afforded pyridine-
KETENE-S,N-ACETALS AS SYNTHETIC INTERMEDIATES FOR HETEROCYCLES. A NOVEL SYNTHESIS OF POLYFUNCTIONALIZED PYRIDINE-2-THIONES
Takahata, Hiroki,Nakajima, Tomoko,Yamazaki, Takao
, p. 1658 - 1661 (2007/10/02)
A new synthesis of polyfunctionalized pyridine-2-thiones (4a-c) by the carbon-carbon bond formation between β-aminothiocarbonyl-α-methylthioenamines (3a-c) derived from ketene-S,N-acetal (1) and malononitrile as a carbon nucleophile is described.In additi
