92508-32-2Relevant articles and documents
Highly enantioselective construction of the α-chiral center of amides via iridium-catalyzed hydrogenation of α,β-unsaturated amides
Lu, Wei-Jing,Hou, Xue-Long
supporting information; experimental part, p. 1224 - 1228 (2009/12/06)
The chiral center at the a-position of amides is installed in excellent enantioselectivity via the iridium-catalyzed asymmetric hydrogenation of αβ-unsaturated amides under mild conditions. Even aliphatic amides are suitable substrates. The presence of a