92520-11-1Relevant academic research and scientific papers
Direct Enamido C(sp2)?H Diphosphorylation Enabled by a PCET-Triggered Double Radical Relay: Access to gem-Bisphosphonates
Cao, Hao-Qiang,Liu, Hao-Nan,Liu, Zhe-Yuan,Ma, Jun-An,Qiao, Bao-Kun,Zhang, Fa-Guang
supporting information, p. 5515 - 5521 (2020/04/27)
Herein we report a novel and straightforward protocol for the construction of valuable gem-BPs by means of proton-coupled electron-transfer (PCET)-triggered enamido C(sp2)?H diphosphorylation. This reaction represents a rare example of realizing the challenging double C?P bond formation at a single carbon atom, thus providing facile access to a broad variety of structurally diverse bisphosphonates from simple enamides under silver-mediated conditions. Initial mechanistic studies demonstrated that the diphosphorylation involves two rounds of PCET-initiated radical relay process.
An efficient synthesis of styrenyl enamides from 4-aryl-2-oxazolidinones in the presence of strong base
Zou, Kaihe,Ye, Jinxing,Wu, Xin-Yan
supporting information, p. 5517 - 5520 (2015/09/21)
Efficient synthesis of styrenyl enamides can be achieved from the corresponding 4-aryl-2-oxazolidinones, 2-thioxooxazolidines, and 2-thioxothiazolidines in the presence of the strong base lithium diisopropylamine. The reaction proceeded efficiently to ach
Optically active cyclopropanols by samarium(II) iodide induced intramolecular reductive cyclisation of β-chlorosubstituted amides
Fadel
, p. 531 - 534 (2007/10/02)
Samarium diiodide promotes under mild conditions, intramolecular reductive cyclisation of β-chloro substituted amides, and leads with an excellent diastereomeric excess and high yield to functionalised optically active cyclopropranols.
Cathodic Reduction of α-Azidostyroles. Electrolytic Studies on Vinylazides, I
Knittel, Dierk
, p. 523 - 532 (2007/10/02)
Cathodic reduction of non-terminal vinylazides on Hg cathodes in the presence of electrophiles gives reasonable yields of N-acylated enamines in an electrochemically totally irreversible reaction.In the presence of added H-donors rather high selectivity f
