92522-01-5Relevant academic research and scientific papers
SYNTHESIS OF 5-HYDROXY- AND 5-ACYLHYDRAZINOPYRAZOLIDINES BY THE REACTION OF &β-SUBSTITUTED HYDRAZIDES WITH &α,&β-UNSATURATED ALDEHYDES AND THEIR BIOLOGICAL ACTIVITY
Zelenin, K. N.,Dovgilevich, A. V.,Bezhan, I. P.,Golubeva, G. A.,Sviridova, L. A.,et al.
, p. 529 - 536 (2007/10/02)
The reaction of β-substituted hydrazides with alkenals (acrolein, methacrolein, crotonaldehyde, and cinnamaldehyde) serves as a method for the synthesis of the corresponding 1-acyl-5-hydroxypyrazolidines and, in a number of cases, 1-acyl-5-acylhydrazinopyrazolidines.Some of the 1-acyl-5-hydroxypyrazolidines obtained have antiphlogistic activity.
