92524-98-6 Usage
Uses
Used in Organic Synthesis:
1H-Pyrazole, 1-methyl-3-(trimethylsilyl)is utilized as a building block in organic synthesis for the creation of various functionalized pyrazole derivatives. Its unique structure allows for the development of novel compounds with potential applications in different industries.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 1H-Pyrazole, 1-methyl-3-(trimethylsilyl)serves as a reagent in chemical reactions, contributing to the synthesis of various pharmaceuticals. Its unique properties enable the development of new drugs with improved therapeutic effects and reduced side effects.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical industry, 1H-Pyrazole, 1-methyl-3-(trimethylsilyl)is employed as a reagent in the synthesis of agrochemicals, such as pesticides and herbicides. Its unique structure allows for the development of more effective and environmentally friendly agrochemicals.
Used in Materials Science:
1H-Pyrazole, 1-methyl-3-(trimethylsilyl)has potential applications in the field of materials science. Its unique structure and properties can be leveraged to develop new materials with specific characteristics, such as improved stability, conductivity, or other desirable properties.
Used in Catalysis:
In the field of catalysis, 1H-Pyrazole, 1-methyl-3-(trimethylsilyl)can be used as a catalyst or a catalyst precursor in various chemical reactions. Its unique structure and properties may enhance the efficiency and selectivity of catalytic processes, leading to more sustainable and cost-effective chemical production methods.
Check Digit Verification of cas no
The CAS Registry Mumber 92524-98-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,5,2 and 4 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 92524-98:
(7*9)+(6*2)+(5*5)+(4*2)+(3*4)+(2*9)+(1*8)=146
146 % 10 = 6
So 92524-98-6 is a valid CAS Registry Number.
92524-98-6Relevant academic research and scientific papers
MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR
-
, (2019/11/04)
This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis by administering such modulators and pharmaceutical compositions, and processes for making such modulators.
Regioselective Halo- and Carbodesilylation of (Trimethylsilyl)-1-methylpyrazoles
Effenberger, Franz,Krebs, Andreas
, p. 4687 - 4695 (2007/10/02)
The isomeric 3-, 4-, and 5-(trimethylsilyl)- as well as the 3,4-, 3,5-, and 4,5-bis(trimethylsilyl)-1-methylpyrazoles (2, 7, 3, 5, 9, and 10, respectively) are obtained by methylation of the corresponding (trimethylsilyl)-1H-pyrazoles or by silylation of Grignard or lithio derivatives of appropriate 1-methylpyrazoles with chlorotrimethylsilane. 5 and 10 are halodesilylated regioselectively by Br2 or ICl in the 4-position, yielding 13 and 15.With addditional bromine, these monobromo compounds suffer exclusively bromodesilylation to give 3,4- and 4,5-dibromo-1-methylpyrazole (14 and 16, respectively).These findings are in accord with the electrophilic substitution reactivity indices for 1-methylpyrazole (8) and with ipso-directing influence of the Me3Si group.The reaction of 5 with I2, unexpectedly, attacks preferentially at the 3-position.Regioselective carbodesilylation in the 5-position is observed in the fluoride-catalyzed reactions of 3, 9, and 10 with carbon electrophiles.The high regiospecificity of this reaction is rationalized in terms of carbanion stabilization at the individual pyrazole positions.
