92525-57-0Relevant academic research and scientific papers
Preparation of Highly Substituted 2-Pyridones by Reaction of Vinyl Isocyanates and Enamines
Rigby, James H.,Balasubramanian, N.
, p. 224 - 228 (1989)
A method for synthesis of highly substituted 2(1H)-pyridones is reported.Vinyl isocyanates, prepared from the corresponding α,β-unsaturated carboxylic acids, undergo cyclization with various enamines to furnish six-membered heterocycles.The methodology is exemplified by numerous examples.Application of this strategy is further illustrated by the synthesis of several aza steroid analogues.
Vinyl Isocyanate Cyclization Reactions in Synthesis. An Expedient Construction of the Octahydrophenanthridinone Ring System
Rigby, James H.,Balasubramanian, N.
, p. 4569 - 4571 (2007/10/02)
The octahydrophenanthridinone ring system is assembled in one step via a thermally induced reaction of vinyl isocyanates and enamines.
