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6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER, also known as 6-FAM-SE, is a fluorescent reagent commonly used for the labeling of peptides, proteins, and nucleotides. It is known for its ability to bind amines and alcohols, making it a versatile tool in various applications.

92557-81-8

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92557-81-8 Usage

Uses

Used in Biochemistry and Molecular Biology:
6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER is used as a fluorescent label for the detection and analysis of peptides, proteins, and nucleotides. Its fluorescent properties allow for the tracking and visualization of these biomolecules in various experimental setups.
Used as an Intracellular pH Probe:
6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER is used as an intracellular pH probe, enabling researchers to monitor and measure the pH levels within cells. This is crucial for understanding cellular processes and the effects of various treatments on cell physiology.
Used in Chemical Synthesis:
6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER is used as a fluorescent label for amines and alcohols in chemical synthesis. This allows for the easy detection and tracking of these functional groups in various chemical reactions and processes.

Check Digit Verification of cas no

The CAS Registry Mumber 92557-81-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,5,5 and 7 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 92557-81:
(7*9)+(6*2)+(5*5)+(4*5)+(3*7)+(2*8)+(1*1)=158
158 % 10 = 8
So 92557-81-8 is a valid CAS Registry Number.
InChI:InChI=1/C25H15NO9/c27-13-2-5-16-19(10-13)34-20-11-14(28)3-6-17(20)23(16)18-9-12(1-4-15(18)24(31)32)25(33)35-26-21(29)7-8-22(26)30/h1-6,9-11,27H,7-8H2,(H,31,32)

92557-81-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-Carboxyfluorescein N-hydroxysuccinimide ester

1.2 Other means of identification

Product number -
Other names (2,5-dioxopyrrolidin-1-yl) 3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:92557-81-8 SDS

92557-81-8Relevant academic research and scientific papers

Synthesis of immunocomponents for the measurement of lead (Pb) by fluorescence polarization immunoassay

Adamczyk, Maciej,Fishpaugh, Jeffrey R.,Heuser, Kevin J.,Ramp, John M.,Reddy, Rajarathnam E.,Wong, Martin

, p. 3093 - 3112 (2007/10/03)

Three novel haptens (5b, 9b, 11b) were synthesized from porphobilinogen (2) and conjugated to bovine serum albumin to afford immunogens (6, 10, 12). Five fluorescent tracers (14, 17, 19, 29, 32) were prepared from porphobilinogen (2), or haptens (9b, 11b, 20b) in >98% purity. The immunogens (6, 10, 12) were utilized for generation of polyclonal antibodies and the best tracer-antibody combination was selected to construct the calibration curve for the measurement of lead.

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