92566-53-5Relevant academic research and scientific papers
Pharmaceutical compositions containing naphthalene-and azanaphthalene-carboxamide derivatives, new naphthalene-and azanaphthalene-carboxamide derivatives and process for their preparation
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, (2008/06/13)
Compounds of the formula: STR1 in which R 1 is C 1-6 alkyl, phenyl, C 3-6 cycloalkyl, phenylalkyl, cycloalkyl-alkyl or STR2 R 3 and R 4 being H or alkyl, R 5 being alkenyl or alkynyl, and the sum of the carbon atoms in R 3, R 4 and R 5 being 2 to 5, R 2 is as defined for R 1 and may also represent STR3 in which n is 0, 1, 2 or 3, it also being possible for R 1 and R 2 to form, with the nitrogen atom to which they are attached, a 5-, 6- or 7-membered heterocyclic radical which can contain another hetero-atom chosen from O and N and which can carry 1 or 2 substituents, Z is phenyl, pyridinyl, thienyl, thiazol-2-yl or substituted phenyl, X and R 0 are H, halogen, C 1-3 alkyl, C 1-3 alkoxy, nitro or CF 3, A represents N or CH and E represents N or CH, some of which are known compounds, are therapeutically useful compounds useful in the treatment of anxiety states or of pulmonary, renal, circulatory or cardiovascular disorders.
