925685-15-0

Upstream product

• 925685-08-1 benzyl 3-(2-hydroxy-5-(ethoxy(diethylphosphonomethyl)phosphinoyl)phenyl)-3-methylbutanoate 
• 141-75-3 butyryl chloride 
• 179015-82-8 diethyl 1-(ethoxyphosphinyl)methylphosphonate 
• 100-39-0 benzyl bromide 
• 925685-07-0 3-(2-hydroxy-5-(ethoxy(diethylphosphonomethyl)phosphinoyl)phenyl)-3-methylbutanoic acid 
• 925685-06-9 6-(ethoxy(diethylphosphonomethyl)phosphinoyl)-3,4-dihydro-4,4-dimethylchromen-2-one 
• 164012-31-1 4,4-dimethyl-6-bromo-2-oxo-chroman 

Downstream Products

• 925685-16-1 3-(2-butyroxy-5-(ethoxy(diethylphosphonomethyl)phosphinoyl)phenyl)-3-methylbutanoic acid 
• 925685-17-2 7-(4-(3-(2-butyroxy-5-(ethoxy(diethylphosphonomethyl)phosphinoyl)phenyl)-3-methylbutanoyl)-3-methylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylic acid 

Relevant academic research and scientific papers

Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections

The present invention relates to phosphonated fluoroquinolones, antibacterial analogs thereof, and methods of using such compounds. These compounds are useful as antibiotics for prevention and/or the treatment of bone and joint infections, especially for the prevention and/or treatment of osteomyelitis.