925688-17-1Relevant articles and documents
Optimization of monocarboxylate transporter 1 blockers through analysis and modulation of atropisomer interconversion properties
Guile, Simon D.,Bantick, John R.,Cooper, Martin E.,Donald, David K.,Eyssade, Christine,Ingall, Anthony H.,Lewis, Richard J.,Martin, Barrie P.,Mohammed, Rukhsana T.,Potter, Timothy J.,Reynolds, Rachel H.,St-Gallay, Stephen A.,Wright, Andrew D.
, p. 254 - 263 (2007/10/03)
We have previously described a novel series of potent blockers of the monocarboxylate transporter, MCT1, which show potent immunomodulatory activity in an assay measuring inhibition of PMA/ionomycin-induced human PBMC proliferation. However, the preferred