92569-10-3Relevant articles and documents
Oxalylhydrazides as oxidation products of analgesic pyrazolinones
Weber,Bresser
, p. 152 - 155 (2007/10/03)
In contrast to antipyrine (1a) and isopropylantipyrine (1b) the amino-substituted pyrazolinones 4-aminoantipyrine (1d), 4-methylaminoantipyrine (1e), 4-isopropylaminoantipyrine (1f) and dipyrone (1g) as well as 4-hydroxyantipyrine (1e) can be cleaved into
Ring Opening of 3(2H)-Pyrazolones by Oxidation with Periodate
Weber, Horst,Wollenberg, Eva
, p. 551 - 553 (2007/10/02)
In contrast to the aminopyrazolones 1 the pyrazolones 3 and 5 are stable against singlet oxygen.However, no difference is observed in reaction of the title compounds 1, 3 and 5 with sodium metaperiodate forming the oxidation products 2, 4 and 6, respectively.The (1)H- and (13)C-nmr-spectra of 4 as well as those of 2 are complex due to the existence of rotameric isomers at room temperature.