38604-70-5Relevant academic research and scientific papers
Oxalylhydrazides as oxidation products of analgesic pyrazolinones
Weber,Bresser
, p. 152 - 155 (2007/10/03)
In contrast to antipyrine (1a) and isopropylantipyrine (1b) the amino-substituted pyrazolinones 4-aminoantipyrine (1d), 4-methylaminoantipyrine (1e), 4-isopropylaminoantipyrine (1f) and dipyrone (1g) as well as 4-hydroxyantipyrine (1e) can be cleaved into
METHYLATION OF N-PHENYL-N'-ACETYLHYDRAZINE WITH DIMETHYL SULFATE
Barinova, V. N.,Voronin, V. G.,Zhestkov, V. P.,Portnov, Yu. N.
, p. 1609 - 1611 (2007/10/02)
The reaction of N-phenyl-N'-acetylhydrazine with dimethyl sulfate in benzene in the presence of a 40percent solution of sodium hydroxide leads to a mixture of N-methyl-N-phenyl-N'-acetylhydrazine (45percent), N,N'-dimethyl-N-phenyl-N'-acetylhydrazine (31percent), and N'-methyl-N-phenyl-N'acetylhydrazine (24percent).The dimethyl derivative is formed through the methylation of N-methyl-N-phenyl-N'-acetylhydrazine by dimethyl sulfate, whereas the other isomer does not react under these conditions.
