925699-36-1

Upstream product

• 50-00-0 formaldehyd 
• 139416-71-0 1-(o-tolyl)prop-2-yn-1-ol 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 1261268-33-0 methyl (E)-3-(1-o-tolylbuta-2,3-dienyloxy)acrylate 
• 1361252-01-8 (S)-2-(o-tolyl)-2,5-dihydrofuran 
• 130552-20-4 trimethyl<1-(2-methylphenyl)-1,3-butadien-3-yl>silane 
• 1345012-74-9 1-methyl-2-(1-(vinyloxy)buta-2,3-dien-1-yl)benzene 

Relevant academic research and scientific papers

Palladium-catalyzed [3+2] annulation of allenyl carbinol acetates with C,N-cyclic azomethine imines

In this paper, a palladium-catalyzed [3+2] annulation of allenyl carbinol acetates with azomethine imines has successfully been developed under mild reaction conditions, affording biologically interesting tetrahydropyrazoloisoquinoline derivatives in high to excellent yields and with excellent stereoselectivity. The reaction follows a tandem [3+2] cycloaddition/allylation/elimination of AcOH pathway. Allenyl carbinol acetates also reacted well with in situ generated azomethine imine under cocatalysis of Ag(i)/Pd(0) catalysts in a similar reaction pathway.

Chiral silver phosphate-catalyzed cycloisomeric kinetic resolution of α-allenic alcohols

A kinetic resolution of α-allenic alcohols is realized through chiral silver phosphate-catalyzed cycloisomerization with high stereoselectivity (selectivity factor up to 189) and tolerance of a variety of functional groups. A mechanistic model is proposed to interpret the origin of the high stereoselectivity and broad substrate scope.