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(2-aminophenyl)-3’-pyridyl sulfide, also known as APS, is a sulfide derivative with the molecular formula C11H10N2S. It is a pale yellow solid that is soluble in organic solvents such as acetone and chloroform. APS is primarily used as a reagent in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. It is also utilized in the production of dyes and pigments. Additionally, APS has been studied for its potential antioxidant and anticancer properties. However, it is important to handle APS with care as it can be toxic and harmful if ingested or inhaled.

92575-22-9

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92575-22-9 Usage

Uses

Used in Organic Synthesis:
APS is used as a reagent in organic synthesis for the preparation of pharmaceuticals and agrochemicals. Its unique chemical structure allows for the formation of various compounds with potential applications in these industries.
Used in Dye and Pigment Production:
APS is utilized in the production of dyes and pigments due to its chemical properties. Its ability to form stable compounds makes it a valuable component in the creation of colorants for various applications.
Used in Pharmaceutical Industry:
APS is used as a reagent in the development of pharmaceuticals. Its potential antioxidant and anticancer properties make it a promising candidate for the creation of new drugs and treatments.
Used in Agrochemical Industry:
APS is used in the production of agrochemicals, where its reactivity and stability contribute to the development of effective products for agricultural applications.
Used in Antioxidant and Anticancer Research:
APS has been studied for its potential antioxidant and anticancer properties. Its unique chemical structure allows for the exploration of its potential use in the development of treatments for various diseases and conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 92575-22-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,5,7 and 5 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 92575-22:
(7*9)+(6*2)+(5*5)+(4*7)+(3*5)+(2*2)+(1*2)=149
149 % 10 = 9
So 92575-22-9 is a valid CAS Registry Number.

92575-22-9Downstream Products

92575-22-9Relevant academic research and scientific papers

Iron-catalyzed S-arylation of benzothiazole with aryl iodides under aqueous medium: Facile synthesis of aryl(2-aminoaryl) sulfides

Lee, Hang Wai,Yung, Ka Fu,Kwong, Fuk Yee

, p. 2743 - 2747 (2014)

A simple route for facile access of aryl(2-aminoaryl) sulfide was reported. With the aid of iron(III) chloride catalyst and diamine ligand, benzothiazole was efficiently S-arylated with various aryl iodides (19 examples) in water under air atmosphere. This operationally simple protocol provides aryl(2-aminoaryl) sulfides in moderate to good yields.

Iron-Catalyzed S-Arylation of Benzothiazole with Aryl Iodides under Aqueous Medium: Facile Synthesis of Aryl(2-aminoaryl) Sulfides

Lee, Hang Wai,Yung, Ka Fu,Kwong, Fuk Yee

, p. 2743 - 2747 (2015/05/05)

A simple route for facile access of aryl(2-aminoaryl) sulfide was reported. With the aid of iron(III) chloride catalyst and diamine ligand, benzothiazole was efficiently S-arylated with various aryl iodides (19 examples) in water under air atmosphere. This operationally simple protocol provides aryl(2-aminoaryl) sulfides in moderate to good yields.

Unexpectedly ligand-free copper-catalyzed C-S cross-coupling of benzothiazole with aryl iodides in aqueous solution

Feng, Yi-Si,Qi, Hong-Xia,Wang, Wei-Cheng,Liang, Yu-Feng,Xu, Hua-Jian

supporting information; experimental part, p. 2914 - 2917 (2012/07/27)

A novel synthetic protocol for 2-aminophenyl sulfide derivatives via the reactions of benzothiazole with aryl iodides was reported for the first time. The reactions were catalyzed by CuCl with tetrabutylammonium hydroxide as the base and water as the solvent without ligand at 50°C or room temperature. A variety of aryl iodides underwent the C-S cross-coupling reaction with benzothiazole to afford smoothly the corresponding products in excellent yield.

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