925913-34-4Relevant academic research and scientific papers
Proteasome inhibition by peptide-semicarbazones
Leban, Johann,Blisse, Marcus,Krauss, Babett,Rath, Sandra,Baumgartner, Roland,Seifert, Markus H.J.
, p. 4579 - 4588 (2008/12/20)
Peptide-semicarbazones derived from Z-Trp-Trp-Phe-aldehyde inhibit the chymotryptic activity of the human proteasome at nanomolar concentrations, but are less active in a NFκB reporter gene assay. Cyclic semicarbazones, in contrast, combine a strong inhib
Inhibitors of cancer cell, T-cell and keratinocyte proliferation
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Page/Page column 13, (2008/06/13)
The invention relates to compounds of the general formula (I) and salts and physiologically functional derivatives thereof, wherein Y is —NRaRb, —NRcC═ONRaRb, —NRcC═SNRaRb/
