925916-15-0Relevant academic research and scientific papers
Metal–Organic Layers Hierarchically Integrate Three Synergistic Active Sites for Tandem Catalysis
Quan, Yangjian,Lan, Guangxu,Shi, Wenjie,Xu, Ziwan,Fan, Yingjie,You, Eric,Jiang, Xiaomin,Wang, Cheng,Lin, Wenbin
supporting information, p. 3115 - 3120 (2020/12/09)
We report the design of a bifunctional metal–organic layer (MOL), Hf12-Ru-Co, composed of [Ru(DBB)(bpy)2]2+ [DBB-Ru, DBB=4,4′-di(4-benzoato)-2,2′-bipyridine; bpy=2,2′-bipyridine] connecting ligand as a photosensitizer and Co(dmgH)2(PPA)Cl (PPA-Co, dmgH=dimethylglyoxime; PPA=4-pyridinepropionic acid) on the Hf12 secondary building unit (SBU) as a hydrogen-transfer catalyst. Hf12-Ru-Co efficiently catalyzed acceptorless dehydrogenation of indolines and tetrahydroquinolines to afford indoles and quinolones. We extended this strategy to prepare Hf12-Ru-Co-OTf MOL with a [Ru(DBB)(bpy)2]2+ photosensitizer and Hf12 SBU capped with triflate as strong Lewis acids and PPA-Co as a hydrogen transfer catalyst. With three synergistic active sites, Hf12-Ru-Co-OTf competently catalyzed dehydrogenative tandem transformations of indolines with alkenes or aldehydes to afford 3-alkylindoles and bisindolylmethanes with turnover numbers of up to 500 and 460, respectively, illustrating the potential use of MOLs in constructing novel multifunctional heterogeneous catalysts.
Recyclable graphite oxide catalyzed Friedel-Crafts addition of indoles to α,β-unsaturated ketones
Vijay Kumar,Rama Rao
supporting information; experimental part, p. 5188 - 5191 (2011/10/12)
The Friedel-Crafts addition of indoles to α,β-unsaturated ketones, and nitro styrenes was studied with graphite oxide as catalyst. Various indole derivatives were synthesized in good to excellent yields. The preparation of graphite oxide catalyst from sim
Iron salt-catalyzed cascade type one-pot double alkylation of indole with vinyl ketones
Kobayashi, Jun-ka,Matsui, Shin-ichiro,Ogiso, Koji,Hayase, Shuichi,Kawatsura, Motoi,Itoh, Toshiyuki
experimental part, p. 3917 - 3922 (2010/07/05)
Indole was reacted with vinyl ketones in the presence of 5-8 mol % of iron (II) tetrafluoroborate or iron (III) perchlorate to give 2,3-dialkylated products; initial alkylation took place at 3-position on the indole ring and subsequent alkylation occurred at 2-position. It was found that the first alkylation proceeded very quickly, while the reaction rate of the second alkylation was very slow. Using this, cascade type synthesis of 2,3-dialkylated-indoles has been accomplished using iron (III)salt as catalyst.
BENZAZEPIN-2(1H)-ONE DERIVATIVES
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Page/Page column 47-48, (2008/06/13)
Compounds of formula (I) and pharmaceutically acceptable salts thereof are agonists at the beta-2 adrenoceptor. They are useful as feed additives for livestock animals.
Thermal rearrangement of indolyl oxime esters to pyridoindoles
Portela-Cubillo, Fernando,Surgenor, Brian A.,Aitken, R. Alan,Walton, John C.
, p. 8124 - 8127 (2008/12/22)
(Chemical Equation Presented) Acyl oximes derived from a variety of indolylalkanones underwent a ring closure sequence during FVP to afford 9H-pyrido[2,3-b]indoles. Unlike UV light promoted reactions of oxime esters, the mechanism is almost certainly not mediated by iminyl radicals but probably involves tautomerism, elimination of acetic acid, and a final electrocyclic ring closure.
Silica-supported sodium sulfonate with ionic liquid: A neutral catalyst system for Michael reactions of indoles in water
Gu, Yanlong,Ogawa, Chikako,Kobayashi, Shu
, p. 175 - 178 (2007/10/03)
(Chemical Equation Presented) A neutral catalytic system for Michael reactions of indoles has been developed by combining silica-supported benzenesulfonic acid sodium salt with hydrophobic ionic liquid in water. An efficient hydrophobic environment could
