925941-01-1

Upstream product

• 925940-89-2 3-[3-(1-hydroxy-ethyl)-isoxazol-5-yl]-benzonitrile 
• 124-63-0 methanesulfonyl chloride 

Relevant academic research and scientific papers

Substituted piperazines as metabotropic glutamate receptor antagonists

The invention relates to compounds of formula I or pharmaceutically acceptable salts or solvates thereof: where Ar1, Ar2, Hy, L, R1, m and n are as defined in the description. The invention also includes pharmaceutical compositions and uses thereof, processes for making the compounds, as well as methods for the medical treatment of mGluR5-mediated disorders.

MGluR5 modulators VI

The present invention is directed to novel compounds, to a process for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds.