926010-58-4

Upstream product

• 252342-46-4 (5Z,13Z)-(2S,3R,4S,8S,9R,10R,11S,12S)-3,9-Bis-(tert-butyl-dimethyl-silanyloxy)-11-(4-methoxy-benzyloxy)-2,4,6,8,10,12-hexamethyl-hexadeca-5,13,15-trien-1-ol 
• 926010-56-2 C₁₈H₂₆O₅ 
• 926010-64-2 C₁₀H₁₈O₄ 
• 926010-65-3 C₂₂H₄₆O₄Si₂ 
• 926010-57-3 C₂₁H₄₆O₃Si₂ 
• 926010-66-4 C₂₉H₅₄O₄Si₂ 
• 926010-54-0 C₄₅H₇₈O₅Si₂ 
• 926010-67-5 C₂₃H₄₀O₄Si 
• 926010-55-1 C₂₃H₃₈O₄Si 
• 133007-95-1 (2S,3R,4S)-5-[(4-methoxybenzyl)oxy]-2,4-dimethylpentane-1,3-diol 
• 256920-81-7 1-[(5Z,13Z)-(2S,3R,4S,8S,9R,10R,11S,12S)-11-(4-methoxybenzoxy)-3,9-bis(tert-butyldimethylsilanyloxy)-2,4,6,8,10,12-hexamethylhexadeca-5,13,15-trienyloxymethyl]-4-methoxybenzene 
• 496035-36-0 (2R,3S,4S)-3-hydroxy-5-(4-methoxybenzyloxy)-2,4-dimethylpentanal 
• 827017-66-3 3,9-bis-(tert-butyl-dimethyl-silanyloxy)-11-(4-methoxy-benzyloxy)-2,4,6,8,10,12-hexamethyl-hexadeca-5,13,15-trienal 

Downstream Products

• 926010-62-0 4-[4,10-bis-(tert-butyl-dimethyl-silanyloxy)-12-(4-methoxy-benzyloxy)-3,5,7,9,11,13-hexamethyl-heptadeca-1,6,14,16-tetraenyl]-6-[2-(tert-butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-1,3-dimethyl-hex-4-enyl]-2,2-dimethyl-[1,3]dioxane 
• 926010-59-5 5,13,19-tris-(tert-butyl-dimethyl-silanyloxy)-1,21-bis-(4-methoxy-benzyloxy)-4,6,12,14,16,18,20,22-octamethyl-hexacosa-2,10,15,23,25-pentaene-7,9-diol 

Relevant academic research and scientific papers

Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol

The design, synthesis, and biological evaluation of a series of hybrids and analogues of the microtubule-stabilizing anticancer agents dictyostatin, discodermolide, and taxol is described. A 22-membered macrolide scaffold was prepared by adapting earlier

Design, synthesis and biological evaluation of a macrocyclic discodermolide/dictyostatin hybrid

A 22-membered macrocyclic discodermolide/dictyostatin hybrid has been designed and synthesised; biological evaluation against a range of human cancer cell lines revealed significant levels of growth inhibition. The Royal Society of Chemistry.