926275-68-5

Basic information

• Product Name: N-Propyl-2-piperidine carboxylic acid
• Synonyms: N-Propyl-2-piperidine carboxylic acid
• CAS NO: 926275-68-5
• Molecular Formula: C9H17NO2
• Molecular Weight: 171.238
• Mol File: 926275-68-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Propyl-2-piperidine carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-Propyl-2-piperidine carboxylic acid(926275-68-5)
• EPA Substance Registry System: N-Propyl-2-piperidine carboxylic acid(926275-68-5)

Safety Data

• Hazardous Substances Data: 926275-68-5(Hazardous Substances Data)

Upstream product

• 123-38-6 propionaldehyde 
• 3105-95-1 pipecolinic acid 

Relevant articles and documents

Method for preparing ropivacaine hydrochloride

The preparation method comprises the following specific steps: 1) reacting (S)- piperidine -2 - formic acid with propionaldehyde in the presence of a reducing agent and an aprotic solvent to obtain the intermediate 1. 2). N. NIn the presence of -dimethylformamide and an aprotic solvent, the intermediate 1 obtained in step 1) and the acylating agent are subjected to an acylation reaction to give an intermediate 2. 3). N. N[-] The intermediate 2 obtained in step 2) and 2 and 6 -dimethylaniline are subjected to a condensation reaction in the presence of dimethylformamide and basic conditions to give an intermediate 3. 4) The intermediate 3 obtained in step 3) is salified with hydrochloric acid to give the ropivacaine hydrochloride crude product. 5) The ropivacaine hydrochloride is purified to obtain ropivacaine hydrochloride. The method has the advantages that the product purity is higher than 99.99%, the synthesis process is mild in reaction condition, simple in preparation process, low in cost, safe and environment-friendly, and is suitable for industrial production.

Heterocyclic acylamide derivative and preparation method and pharmaceutical application thereof

The invention relates to a heterocyclic acylamide derivative and a preparation method and pharmaceutical application thereof, in particular to a heterocyclic acylamide derivative shown as a general formula (I) or a stereoisomer and a pharmaceutically-acce

Substituted piperidine amide derivative, preparation method thereof, and application of derivative to pharmacy

The invention relates to a substituted piperidine amide derivative as shown in a general formula (I) or a stereisomer and pharmaceutically acceptable salt thereof, a preparation method of the derivative, medicinal combination as well as application of the derivative to the aspects of local anaesthesia or analgesia. The definition of each group of the general formula (I) is consistent with that of the description. (The general formula (I) is as shown in the description).