926290-19-9

Upstream product

• 147782-81-8 (2S,4R)-1-<(tert-Butyldimethylsilyl)oxy>-2,4-dimethylpentanal 
• 147782-80-7 (2S,4R)-5-(tert-butyl(dimethyl)silyloxy)-2,4-dimethyl-1-pentanol 
• 121712-54-7 (2E,4E)-N-methoxy-N-methyl-hexa-2,4-dienamide 
• 903504-39-2 3-hydroxy-5-methyl-2-vinyl-7-oxa-bicyclo[4.1.0]heptane-3-carboxylic acid methyl ester 
• 903504-31-4 1-hydroxy-5-methyl-2-vinyl-cyclohex-3-enecarboxylic acid methyl ester 
• 903504-28-9 (2R,3E,5E)-1-(phenylthio)hepta-3,5-dien-2-ol 
• 903504-38-1 (3E,5E)-1-(phenylthio)hepta-3,5-dien-2-one 
• 926289-97-6 5-(4-methoxy-benzyloxy)-2,4-dimethyl-hept-6-enal 
• 903504-33-6 11-methyl-8-triethylsilanyloxy-9-vinyl-2,6-dioxa-tricyclo[5.2.2.0^1,5]undec-4-en-3-one 
• 926290-18-8 tert-butyl-[5-(4-methoxy-benzyloxy)-2,4-dimethyl-hept-6-enyloxy]-dimethyl-silane 
• 903504-30-3 7a-hydroxy-6-methyl-3-phenylsulfanylmethyl-3a,6,7,7a-tetrahydro-3H-isobenzofuran-1-one 
• 926290-07-5 8-hydroxy-11-methyl-9-vinyl-2,6-dioxa-tricyclo[5.2.2.0^1,5]undec-4-en-3-one 
• 903504-32-5 3-acetoxy-5-methyl-2-vinyl-7-oxa-bicyclo[4.1.0]heptane-3-carboxylic acid methyl ester 
• 903504-29-0 6-methyl-3-phenylsulfanylmethyl-3a,6,7,7a-tetrahydro-3H-isobenzofuran-1-one 

Relevant academic research and scientific papers

Total synthesis of abyssomicin C, atrop-abyssomicin C, and abyssomicin D: Implications for natural origins of atrop-abyssomicin C

In this article, the total syntheses of the antibiotic abyssomicin C (1) and its biologically inactive sibling abyssomicin D (3) are described. A number of unforseen roadblocks in our synthetic plan encouraged innovation, which culminated in the discovery