92642-15-4

Basic information

• Product Name: 6-acetyl-10-methylisoalloxazine
• Synonyms: 6-acetyl-10-methylisoalloxazine
• CAS NO: 92642-15-4
• Molecular Weight: 270.247
• Mol File: 92642-15-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-acetyl-10-methylisoalloxazine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-acetyl-10-methylisoalloxazine(92642-15-4)
• EPA Substance Registry System: 6-acetyl-10-methylisoalloxazine(92642-15-4)

Safety Data

• Hazardous Substances Data: 92642-15-4(Hazardous Substances Data)

Upstream product

• 7463-31-2 3-Acetamidoacetophenone 

Relevant articles and documents

Semisynthetic Enzymes: Characterization of Isomeric Flavopapains with Widely Different Catalytic Efficiencies

Flavopapain 6 has been prepared by alkylation of the active site cysteine-25 of papain with 8α-(bromoacetyl)-10-methylisoalloxazine.This semisynthetic enzyme was shown to serve as a catalyst for the oxidation of dihydronicotinamides, exhibiting saturation kinetics and up to 600-fold rate accelerations relative to a model flavin.This is contrasted to the behavior of flavopapain 9, the product of the modification of papain with 6α-(bromoacetyl)-10-methylisoalloxazine.In this case no catalytic rate enhancement compared to the behavior of a model compound is observed.Since the two isoalloxazines are isomeric, the differences in the activities of the semisynthetic enzymes are interpreted in terms of differences in the geometry of the flavin at the active site.It is also noted that flavopapain 6 can exhibit some chiral discrimination toward optically active dihydronicotinamides.