92666-05-2

Basic information

• Product Name: 1-(p-Tosyloxy)-2-pentyne
• Synonyms: 1-(p-Tosyloxy)-2-pentyne
• CAS NO: 92666-05-2
• Molecular Formula: C₁₂H₁₄O₃S
• Molecular Weight: 238.30276
• Mol File: 92666-05-2.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(p-Tosyloxy)-2-pentyne(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(p-Tosyloxy)-2-pentyne(92666-05-2)
• EPA Substance Registry System: 1-(p-Tosyloxy)-2-pentyne(92666-05-2)

Safety Data

• Hazardous Substances Data: 92666-05-2(Hazardous Substances Data)

Upstream product

• 6261-22-9 pent-2-yn-1-ol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1041847-77-1 [NMe₂(2-pentynyl)(CH=C(CH₃)2)][OTS] 
• 90780-55-5 (±)-(4Z,8E,10Z,13Z,16Z,19Z)-7-hydroxydocosa-4,8,10,13,16,19-hexaenoic acid 
• 67548-36-1 (2E,5Z)-Octa-2,5-dien-1-ol 
• 72561-88-7 (Z,Z,Z)-3,6,9-Octadecatriene 
• 5871-06-7 1-bromotetradeca-2,5,8,11-tetrayne 
• 5871-10-3 2,5,8,11-tetradecatetrayne-1-ol 
• 34498-25-4 1-bromo-2,5,8-undecatriyne 
• 1558-79-8 2,5-octadiynyl bromide 
• 194721-53-4 1-tosyloxy-2,5,8-undecatriyne 
• 35378-82-6 2,5,8-undecatriyne-1-ol 
• 282720-95-0 N-[2-(3-methoxy-4-pent-2-ynyloxy-phenyl)-ethyl]-formamide 
• 172659-63-1 1-(2-Benzyl-1-phenyl-hex-3-yne-2-sulfonyl)-propan-2-one 
• 172659-75-5 C₂₀H₂₂O₂S 
• 104188-11-6 (4Z,7Z)-4,7-decadien-1-ol 

Relevant articles and documents

Enantioselective Synthesis of 7(S)-Hydroxydocosahexaenoic Acid, a Possible Endogenous Ligand for PPARα

We report the first total synthesis of the polyunsaturated fatty acid 7-hydroxydocosahexaenoic acid (7-HDHA) in racemic form and the enantioselective synthesis of 7-(S)-HDHA. Both syntheses follow a convergent approach that unites the C1-C9 and C10-C22 fragments using Sonogashira coupling and Boland reduction as key steps. These syntheses enabled the unambiguous characterization of this natural product for the first time and helped establish 7(S)-HDHA as a possible endogenous ligand for peroxisome proliferator-activated receptor alpha.

A tea canker-worm pheromone (Z, Z, Z) - 3, 6, 9 - triene synthetic method of eighteen carbon (by machine translation)

The invention relates to a natural [...] pheromone component novel synthesis method, in particular relates to a tea canker-worm pheromone (Z, Z, Z) - 3, 6, 9 - eighteen carbon triene synthetic method, it has [...], is non-toxic and harmless, which belongs to the field of drug synthesis. The invention uses inexpensive and easily obtained a halopropynyl alcohol as the reaction of the starting material, in order to iodo reagent catalytic coupling reaction as a key step, after six-step reaction, smooth synthetic tea canker-worm pheromone (Z, Z, Z) - 3, 6, 9 - eighteen carbon triene, the operation is simple, low cost, easily obtained and cheap materials, mild reaction conditions, high yield, the large scale preparation. (by machine translation)

Catalytic Hydroalkylation of Allenes

We have developed a catalytic method for the hydroalkylation of allenes using alkyl triflates as electrophiles and silane as a hydride source. The reaction has an excellent substrate scope and is compatible with a wide range of functional groups, including esters, aryl halides, aryl boronic esters, sulfonamides, alkyl tosylates, and alkyl bromides. We found evidence for a reaction mechanism that involves unusual dinuclear copper ally complexes as catalytic intermediates. The unusual structure of these complexes provides a rationale for their unexpected reactivity.