92693-35-1Relevant academic research and scientific papers
A new one-step strategy for the stereochemical assignment of acyclic 2- and 3-sulfanyl-1-alkanols using the CD exciton chirality method
Weckerle, Bernhard,Schreier, Peter,Humpf, Hans-Ulrich
, p. 8160 - 8164 (2007/10/03)
A new one-step strategy is described for the stereochemical assignment of acyclic 2- and 3-sulfanyl-1-alkanols using the CD exciton chirality method. Using the 9-anthroate chromophore for the derivatization of both functional groups, the resulting bisignate CD curves unequivocally allow the determination of the stereochemistry from a single CD measurement. The usefulness of the new method is demonstrated using synthesized optically pure 3-sulfanyl-1-hexanols and 2-sulfanyl-1-hexanols as model compounds. The developed microscale method is also useful for the stereochemical assignment of 1,2- and 1,3-diols. To our knowledge this is the first application of the CD exciton chirality method to acyclic 2- and 3-sulfanyl-1-alkanols.
Enantioselective Synthesis of (+)- and (-)-cis-2-methyl-4-propyl-1,3-oxathiane and their Olfactive Properties
Pickenhagen, Wilhelm,Broenner-Schindler, Helene
, p. 947 - 952 (2007/10/02)
The enantioselective synthesis of (+)- and (-)-cis-2-methyl-4-propyl-1,3-oxathiane 8 and 9 from (E)-2-hexen-1-ol (1) as common starting material is described.The two enantiomeric forms exhibit different organoleptic properties.
