92714-82-4Relevant academic research and scientific papers
Convenient Synthesis of 3-Aminocoumarin Derivatives by the Condensation of 1,4-Diacetyl- or 3-Substituent-2,5-piperazinediones with Various Salicylaldehyde Derivatives
Shin, Chung-gi,Nakajima, Yoshiharu,Haga, Toshiya,Sato, Yoshiaki
, p. 3917 - 3924 (1986)
The condensation of 1,4-diacetyl- or 3-substituted 2,5-piperazinediones (PDO) with various salicylaldehyde derivatives in the presence of a base, such as potassium t-butoxide or triethylamine, was found to give two extremely different kind of products: 1-acetyl-3-arylmethylene-PDO and 3-(acylamino)coumarin derivatives.The former, which has a (Z)-geometric structure, was readily converted to the latter by irradiation.Furthermore, the conversion mechanism and the structural confirmation are discussed.
FACILE SYNTHESIS AND CONVERSION OF MAIN SKELETON OF ASPIROCHLORIN TO 3-AMINOCOUMARIN DERIVATIVES
Shin, Chung-gi,Nakajima, Yoshiharu,Sato, Yoshiaki
, p. 1301 - 1304 (2007/10/02)
The condensation of 1,4-diacetyl-2,5-piperazinedione with salicylaldehyde gave 1-acetyl-(Z)-3-salicylidene-2,5-piperazinedione and 3-(N-acetylglycyl)aminocoumarin by ca. 1 : 1 ratio.The former was readily converted with t-BuOCl into spiro derivative which has a main skeleton of aspirochlorin.
