927384-43-8

Basic information

• Product Name: 2-(3-Bromophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborine
• Synonyms: 2-(3-Bromophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborine;3-Bromo-1-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)benzene;2-(3-Bromophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborine
• CAS NO: 927384-43-8
• Molecular Formula: C₁₆H₁₂BBrN₂
• Molecular Weight: 322.99488
• Mol File: 927384-43-8.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 0-10°C
• CAS DataBase Reference: 2-(3-Bromophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Bromophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborine(927384-43-8)
• EPA Substance Registry System: 2-(3-Bromophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborine(927384-43-8)

Safety Data

• Hazardous Substances Data: 927384-43-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-(3-Bromophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborine is used as a building block for the synthesis of complex organic compounds. Its unique structure allows for the creation of a variety of molecules with potential applications in different fields.
Used in Medicinal Chemistry:
2-(3-Bromophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborine is used as a pharmaceutical agent for exploring its biological activities and potential therapeutic properties. Research on 2-(3-Bromophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborine and its derivatives is ongoing to determine its full potential in the field of medicine.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(3-Bromophenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborine is used as a starting material for the development of new drugs. Its diverse biological activities and potential as a pharmaceutical agent make it a valuable component in drug discovery and design processes.

Upstream product

• 1214264-88-6 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine 
• 591-19-5 m-Bromoaniline 
• 89598-96-9 (3-bromophenyl)boronic acid 
• 479-27-6 naphthalene-1,8-diamine 

Downstream Products

• 1008097-01-5 3-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)-4'-methoxy-1,1'-biphenyl 
• 1614245-82-7 7-ethyl-4-[4'-(methylsulfonyl)biphenyl-3-yl]-7H-imidazo[4,5-c]pyridazine 
• 1614246-70-6 (3-(7-ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)benzene)boronic acid 
• 950511-17-8 1-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene 

Relevant articles and documents

Direct transformation from arylamines to aryl naphthalene-1,8-diamino boronamides: A metal-free sandmeyer-type process

A direct metal-free transformation from arylamines to aryl naphthalene-1,8-diamino boronamides, a type of masked boronic acid, has been developed based on Sandmeyer-type reactions. A nonsymmetrical diboron reagent, B(pin)-B(dan), was utilized as the boryl

IMIDAZOPYRIDAZINE DERIVATIVES AS MODULATORS OF THE GABAA RECEPTOR ACTIVITY.

The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R and R6 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.

Chemical Compounds

The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.

Boron-masking strategy for the selective synthesis of oligoarenes via iterative Suzuki-Miyaura coupling

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