927396-48-3

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 927396-54-1 (S)-4-[(4R)-2-(4-methoxyphenyl)-[1,3]dioxan-4-yl]-2-methylbutan-1-ol 
• 927396-45-0 (2R,5S,6R)-6-(3-benzyloxy-propyl)-5-methyl-5,6-dihydro-2H-pyran-2-carboxylic acid methyl ester 
• 927396-36-9 (2R,5S,6R)-6-(3-benzyloxy-propyl)-2-methoxy-5-methyl-tetrahydro-pyran-2-carbaldehyde 
• 927396-46-1 (5S,6R)-6-(3-benzyloxy-propyl)-5-methyl-5,6-dihydro-4H-pyran-2-carboxylic acid methyl ester 
• 927396-59-6 (2R,5S,6R)-6-(3-benzyloxy-propyl)-2-methoxy-5-methyl-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 5470-84-8 4-benzyloxybutanal 
• 927396-55-2 (E)-(2S,5S)-7-[(4R)-2-(4-methoxyphenyl)-[1,3]dioxan-4-yl]-3,5-dimethyl-hept-3-en-2-ol 
• 927396-43-8 (E)-(S)-7-[(4R)-2-(4-methoxyphenyl)-[1,3]dioxan-4-yl]-3,5-dimethyl-hept-3-en-2-one 
• 927396-58-5 (S)-4-[(4R)-2-(4-methoxyphenyl)-[1,3]dioxan-4-yl]-2-methylbutyraldehyde 
• 927396-47-2 [(2E,9Z)-(1S,4S,7R)-10-[(2R,5S,6R)-6-(3-benzyloxypropyl)-2-methoxy-5-methyl-tetrahydro-pyran-2-yl]-7-(4-methoxybenzyloxy)-1,2,4-trimethyl-deca-2,9-dienyloxy](tert-butyl)(dimethyl)silane 
• 927396-56-3 (E)-(3R,6S,9S)-9-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-6,8-dimethyl-dec-7-en-1-ol 
• 927396-57-4 [(E)-(1S,4S,7R)-9-bromo-7-(4-methoxy-benzyloxy)-1,2,4-trimethyl-non-2-enyloxy]-tert-butyl-dimethyl-silane 
• 927396-44-9 tert-butyl-{(E)-(1S,4S)-6-[(4R)-2-(4-methoxyphenyl)-[1,3]dioxan-4-yl]-1,2,4-trimethyl-hex-2-enyloxy}dimethylsilane 

Downstream Products

• 115566-02-4 bistramide A 

Relevant academic research and scientific papers

Total synthesis of bistramide A

(Chemical Equation Presented) An asymmetric synthesis of the marine metabolite bistramide A is reported. The synthesis relies on the utility of three different organosilane reagents to construct all principle fragments and 8 of the 11 stereogenic centers of the natural product.

Stereoselective total synthesis of bistramide A

(Chemical Equation Presented) A highly stereoselective and convergent total synthesis of bistramide A is described. The salient feature of this synthesis is the construction of the spiroketal subunit by hydrolysis of dialkylated tosylmethyl isocyanide derivative derived via alkylation of TosMIC with suitably substituted halohydrin derivatives.