92747-18-7Relevant academic research and scientific papers
Ketyl-allene cyclizations promoted by samarium(II) iodide
Molander, Gary A.,Cormier, Elizabeth Pollina
, p. 2622 - 2626 (2007/10/03)
(Chemical Equation Presented) Samarium(II) iodide has proven to be an effective reagent for intramolecular reductive coupling Sreactions. Previous investigations of intramolecular ketyl-olefin coupling reactions provided carbocycles in excellent yield and good diastereoselectivity. This method has been extended to ketyl cyclizations with allenes. Substrates leading to both carbocycles and heterocycles in a selective manner are explored.
