92754-18-2

Upstream product

• 1779-81-3 4,5-Dihydro-thiazol-2-ylamin 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 6692-20-2 2-(2-imino-thiazolidin-3-yl)-1-(4-methoxy-phenyl)-ethanone; hydrobromide 

Downstream Products

• 90032-35-2 6-(4-hydroxyphenyl)-2,3-dihydro-imidazo[2,1-b]thiazole 
• 115859-05-7 4-[6-(4-Methoxy-phenyl)-2,3-dihydro-imidazo[2,1-b]thiazol-5-yl]-4H-pyridine-1-carboxylic acid ethyl ester 
• 115859-04-6 5-<1-(ethoxycarbonyl)-1,4-dihydro-4-pyridyl>-6-phenylimidazo<2,1-b>thiazoline 

Relevant academic research and scientific papers

Synthetic and Mechanistic Studies on the Preparation of Pyridyl-Substituted Imidazothiazoles

A new method is presented for the introduction of the 4'-pyridyl substituent into 6-aryl-2,3-dihydroimidazothiazoles.The method involves treatment of the imidazothiazolines with the reactive complex of pyridine and ethyl chloroformate and oxidative deethyl carboxylation of the dihydropyridine adducts formed.Sulfur in refluxing mesitylene was found most suitable for the latter reaction, but chromium trioxide in pyridine or KtBuO and air were also effective.

5,6-Diaryl-2,3-dihydroimidazothiazoles: A New Class of Immunoregulatory Antiinflammatory Agents

A series of substituted 5,6-diaryl-2,3-dihydroimidazothiazoles were synthesized and evaluated in the rat adjuvant-induced arthritis and mouse oxazolone-induced contact sensitivity assays to determine the potential of these compounds for use as immu

Substituted 6-phenylimidazo[2,1-b]]thiazoles and thiazolines as potential cardiotonic agents

A series of phenylimidazo[2,1-b]thiazoles and thiazolines bearing one or two methoxy groups in different positions of the phenyl ring was synthesized and tested on isolated guinea pig atria. Two compounds showed a strong positive inotropic activity.