927652-22-0

Upstream product

• 927652-20-8 N⁴-benzoyl-2'-O-(2-methoxyethyl)-3'-O-(tert-butyldimethylsilyl)-5'-O-dimethoxytritylcytidine 
• 107-31-3 Methyl formate 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 223777-16-0 2'-O-(2-methoxyethyl)cytidine 
• 93-97-0 benzoic acid anhydride 
• 251647-49-1 C₄₀H₄₁N₃O₉ 

Downstream Products

• 927652-24-2 N⁴-benzoyl-2'-O-(2-methoxyethyl)-3'-O-(tert-butyldimethylsilyl)-5'-O-dimethoxytrityl-6-vinylcytidine 

Relevant academic research and scientific papers

Exploring the synthesis of masked phosphoramido 6-vinylcytidine derivatives as building blocks for cross-linking oligonucleotides

In the present work the synthesis of building blocks (2a,b), bearing a masked form of the reactive vinyl group bound to the C-6 position of a cytidine derivative, has been studied. The understanding of byproduct formation together with conformational considerations let us to plan a straightforward approach for the synthesis of the target compounds.