927804-63-5

Usage

Uses

Used in Pharmaceutical Industry:
Furo[2,3-c]pyridine-2-carboxylic acid, 3-[[(trifluoroMethyl)sulfonyl]oxy]-, ethyl ester is used as an intermediate in the synthesis of pharmaceuticals for its potential biological activity and reactivity.
Used in Agrochemical Industry:
Furo[2,3-c]pyridine-2-carboxylic acid, 3-[[(trifluoroMethyl)sulfonyl]oxy]-, ethyl ester is used as an intermediate in the synthesis of agrochemicals for its potential applications in developing new pesticides or other agricultural products.

Upstream product

• 358-23-6 trifluoromethanesulfonic anhydride 
• 106531-50-4 Ethyl 3-Hydroxyfuro<2,3-c>pyridine-2-carboxylate 
• 18343-02-7 Ethyl 2-(4-Ethoxycarbonyl-3-pyridyloxy) acetate 
• 10128-71-9 3-hydroxyisonicotinic acid 
• 18342-97-7 ethyl 3-hydroxyisonicotinate 
• 358-23-6 trifluoromethylsulfonic anhydride 

Downstream Products

• 1453175-37-5 furo[2,3-c]pyridine-2-carboxylic acid 4-(1-isobutylpiperidine-4-sulfinyl)benzylamide 
• 1453173-84-6 N-[(4-tetrahydropyran-4-ylsulfonylphenyl)methyl]furo[2,3-c]pyridine-2-carboxamide 
• 1453174-07-6 N-[[4-[(1-tetrahydropyran-4-yl-4-piperidyl)sulfonyl]phenyl]methyl]furo[2,3-c]pyridine-2-carboxamide 
• 465531-08-2 furo[2,3-c]pyridine-2-carbonyl chloride 
• 1453176-78-7 furo[2,3-c]pyridine-2-carboxylic acid benzylamide 
• 1453176-79-8 4-{[(furo[2,3-c]pyridine-2-carbonyl)-amino]-methyl}-benzenesulfonyl chloride 
• 1448536-37-5 N-{[4-(piperidine-1-sulfonyl)phenyl]methyl}furo[2,3-c]pyridine-2-carboxamide 
• 1454284-75-3 N-(4-(6-methylpyridin-3-ylsulfonyl)benzyl)furo[2.3-c]pyridine-2-carboxamide 
• 1454284-57-1 furo[2,3-c]pyridine-2-carboxylic acid 4-(tetrahydropyran-4-ylsulfamoyl)benzylamide 
• 1454250-96-4 (R)-N-([5-[(3,5-difluorobenzene)sulfinyl]pyridin-2-yl]methyl)furo[2,3-c]pyridin-2-carboxamide 
• 1454250-97-5 (S)-N-([5-[(3,5-difluorobenzene)sulfinyl]pyridin-2-yl]methyl)furo[2,3-c]pyridin-2-carboxamide 
• 1454250-93-1 N-([5-[(3,5-difluorobenzene)sulfinyl]pyridin-2-yl]methyl)furo[2,3-c]pyridin-2-carboxamide 
• 1454250-90-8 furo[2,3-c]pyridin-2-carboxylic acid [5-(3-trifluoromethylbenzenesulfonyl)pyridin-2-ylmethyl]amide 
• 1362160-47-1 sodium 4-((furo[2,3-c]pyridine-2-carboxamido)methyl)benzenesulfinate 

Relevant academic research and scientific papers

PYRIDINYL AND PYRIMIDINYL SULFOXIDE AND SULFONE DERIVATIVES

Disclosed are certain pyridinyl and pyrimidinyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds and methods of treatment using such compounds.

AMIDO SPIROCYCLIC AMIDE AND SULFONAMIDE DERIVATIVES

Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

AMIDO-BENZYL SULFOXIDE DERIVATIVES

The present invention relates to certain amido-benzyl sulfoxide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment of an NAMPT-mediated disease or condition in a subject, selected from solid or liquid tumor, rheumat

ALKYL-AND DI-SUBSTITUTED AMIDO-BENZYL SULFONAMIDE DERIVATIVES

The present invention relates to certain alkyl- and di-substituted amido-benzyl sulfonamide compounds, pharmaceutical compositions comprising such compounds, and to methods of treatment of NAMPT-mediated disorders, such as diabetes, rheumatoid arthritis,

AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES

The present invention relates to certain amido-benzyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

AMIDO-BENZYL SULFONE AND SULFONAMIDE DERIVATIVES

Disclosed are certain amido-benzyl sulfone and sulfonamide compounds, pharmaceutical compositions comprising such compounds, land methods of treatment using such compounds.

The discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors

Virtual and high-throughput screening identified imidazo[1,2-a]pyrazines as inhibitors of B-Raf. We describe the rationale, SAR, and evolution of the initial hits to a series of furo[2,3-c]pyridine indanone oximes as highly potent and selective inhibitors

RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF

Compounds of Formulas (I), (IIA) and (IIIA) are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using compounds of Formulas (I), (IIA) and (IIIA) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Raf inhibitor compounds and methods of use thereof

Compounds of Formula I are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.