928014-70-4Relevant academic research and scientific papers
Catalytic asymmetric syntheses of α-amino and α-hydroxyl acid derivatives
Han, Xiaojun,Jiang, Xiang-Jun,Civiello, Rita L.,Degnan, Andrew P.,Chaturvedula, Prasad V.,Macor, John E.,Dubowchik, Gene M.
experimental part, p. 3993 - 3996 (2009/10/01)
(Chemical Equation Presented) Herein we report the first room temperature Heck reaction of aryl bromides and CH2=C(NHP)CO2Me (P = Boc or CBz) to form ArCH=C(NHP)CO2Me, which are then used for the asymmetric syntheses of α-
CGRP antagonists
-
Page/Page column 14, (2010/11/26)
The present invention encompasses compounds of Formula I which are antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and t
